You may already know that magnesium is one of the top supplements for healthy aging, but its benefits go beyond supporting you in your golden years. “It’s essential for all stages of life,” says Andrea Wong, Ph.D., senior vice president for scientific and regulatory affairs at the Council for Responsible Nutrition (CRN).
420 FILE – The United States government is likely to end the designation of marijuana as a dangerous narcotic sometime this year, potentially marking one of the biggest federal decisions on the classification of the drug in decades. The U.S. Food and Drug Administration determined that marijuana is less harmful than, say, opioids and other substances, prompting the Biden administration to announce it would “reschedule” cannabis from a Schedule I—which is what the most dangerous drugs are classified as—to a Schedule III drug, commensurate with anabolic steroids and ketamine.
FYI, I’m not against cannabis for medicinal purposes. Especially since I can’t even get a prescription for any painkillers. I could rant about it, but I won’t.
The FDA has agreed to delete and never republish several social-media posts suggesting that ivermectin, a drug that some doctors used to treat COVID-19, is for animals and not humans.
While the FDA still does not approve of using ivermectin to treat COVID, it settled Thursday a lawsuit brought by three doctors who sued it, as well as the Department of Health and Human Services and its secretary, Xavier Becerra, and FDA secretary Robert Califf. All parties have settled.
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At its website as of Friday, the FDA still is not recommending it for COVID and says large doses are dangerous and that prescriptions should be filled by a pharmacy and taken exactly as prescribed.
The FDA declined to respond to Kennedy’s assertion, though it reiterated that it “has not changed its position that currently available clinical trial data do not demonstrate that ivermectin is effective against COVID-19. The agency has not authorized or approved ivermectin for use in preventing or treating COVID-19.”
I honestly don’t know what difference this’ll make. 🤷🏼♀️
“CMS has issued guidance to Medicare Part D plans stating that anti-obesity medications (AOMs) that receive FDA approval for an additional medically accepted indication can be considered a Part D drug for that specific use,” the spokesperson added, specifying that drugs that are FDA-approved for only weight loss do not fall under this consideration.
Wegovy, Rybelsus, and Ozempic, are the different brand names for Semaglutide.They have a black box warning for Medullary thyroid cancer.* 🤦🏼♀️
A group of 400 Israeli survivors of the October 7 Hamas attack, including civilians, released hostages, and soldiers, could be offered MDMA-assisted psychotherapy in a potentially trailblazing study to commence later this year.
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“Our goal is to create a therapy model that can serve universally, with the intention and prayer to help people,” said Dr. Keren Tzarfaty, CEO and co-founder of MAPS Israel, which is already running trials evaluating MDMA-assisted therapy for the treatment of post-traumatic stress disorder, depression, and eating disorders. “We hope it will demonstrate high levels of safety and effectiveness and enable us to offer the program in other places over the region and the world, not only to treat PTSD, but to help people open their hearts and expand their minds.”
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Dr. Rick Doblin, founding president of the U.S.-based MAPS and a longtime advocate for using psychedelic therapy in the Israeli–Palestinian conflict, said that the study would serve as a seminal piece of research into whether psychedelic-assisted therapy can help large groups of traumatized people.
“. . . if the major media picks up on this story, they will have the chance to report on what arguably is the worst—and most harmful—scandal in American medical history”
Historically, there have always been some patients who report that any treatment for depression—including bloodletting—has worked for them, but science demands that for a treatment to be deemed truly effective, it must work better than a placebo or the passage of time without any treatment. This is especially important for antidepressant drugs—including Prozac, Zoloft, and other selective serotonin reuptake inhibitors (SSRIs), as well as Effexor, Cymbalta, and other serotonin and norepinephrine reuptake inhibitors (SNRIs)—because all of these drugs have uncontroversial troubling side effects.
Hundreds of Biden administration employees and federal staffers from more than two dozen agencies are set to walk off the job next week in protest of the White House’s handling of the Middle East crisis.
Yet one glaring problem remains. Despite promising clinical results, no one knows exactly how psychedelic drugs work in the brain. Examining their actions on brain cells isn’t just an academic curiosity. It could give rise to variants that maintain antidepressant properties without the high. And because hallucinogens substantially alter our perception [management?!] of the world, they could be powerful toolsfor investigating the neurobiology behind consciousness.
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This year, scientists found another common theme—psychedelics seem to “reset” the brain to a more youthful state, at least in mice. Like humans, mice have an adolescent critical period, during which their brains are highly malleable and can easily rewire neural circuits, but the window closes after adulthood.
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An earlier study showed that MDMA reopens the critical window in adult mice, so that they change their “personality.” Mice raised alone are often introverted and prefer to keep to themselves in adulthood. A dose of MDMA increased their willingness to snuggle with other mice—essentially, they learned to associate socializing with happiness, concluded the study.
It’s not that surprising. MDMA is well-known to promote empathy and bonding. The new study, by the same team, extended their early results to four psychedelics that don’t trigger fuzzy feelings—LSD, ketamine, psilocybin, and ibogaine. Similar to MDMA, adult mice raised alone changed their usual preference for solitude when treated with any of the drugs. Because habits are hard to change in adulthood—for mice and men—the drugs may have reopened the critical period, allowing the brain to more easily rewire neural connections based on new experiences.
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These are just early results. But psychedelic research is gaining a new ally—artificial intelligence. Algorithms that predict protein structure, combined with rational drug design, could generate psychedelics that retain their psychiatric benefits without the high.
Ms. Cat’s Chronicles 
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